Alpha lipoic acid (ALA), also known as thioctic acid, is an eight-carbon organosulfur compound derived from caprylic acid (octenoic acid). (ii) Other natural polymers have also been gaining attention as potential adsorbents of heavy metals, such as algal polysaccharides alginate [39] and chlorella [40]. This is a substantial difference. Garlic prevented cadmium-induced kidney damage [44] and decreased the oxidative damage due to lead in rats [45]. garlic [42]) and brassicas (e.g., broccoli [43]) have been suggested for effects on glutathione, with hopes for symptomatic improvement and enhanced excretion. I'm intrigued by Lipoic Acid as a potential chelator for mercury , as I suffer from chronic mercury toxicity. Worth the try though i suppose. Alpha-lipoic acid or ALA is a naturally occurring compound that's made in the body. Therefore, ALA supplements are preferably taken on an empty stomach to benefit of the acidic stomach pH. Optim-ALA Optimized Alpha Lipoic Acid utilizes two of the best, most bioavailable forms of R-ALA paired with sesame extract. Why do you think you have mercury toxicity? Therefore, the nutrient alpha lipoic acid should be clinically tested … Alpha-lipoic acid is a natural antioxidant that can be found in potatoes, spinach, broccoli, liver, kidney, and yeast. 4.5 out of 5 stars 6. Insights on the Use of α-Lipoic Acid for Therapeutic Purposeshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC672318Here is a recent paper explaining what the researchers have tried using it for.Edit to add this quote from above paper. reddit. I'm intrigued by Lipoic Acid as a potential chelator for mercury, as I suffer from chronic mercury toxicity. It may be administered intravenously, in creams, and via nebulizer. Press question mark to learn the rest of the keyboard shortcuts, Lipoic Acid as a potential chelator for mercury, the literature shows a half-life of just over 30 minutes. Optim-ALA Optimized Alpha Lipoic Acid is a highly bioavailable alpha lipoic acid supplement from Natrium Health, the sister company of Nootropics Depot. for evidence-based support, only the Cutler Therapy comes up. Alpha-lipoic acid may have been combined with other plants or extracts in a specific preparation to treat … Without Alpha-lipoic acid, free radicals will form a chemical reaction that can lead to the emergence of diseases, such as stroke. … ALA is also beneficial in combating damages and infections that attack vital organs. R-Lipoic Acid is the most active isomer of alpha-lipoic acid, which is a versatile antioxidant. As long as you're healthy, the body can produce all the ALA it needs for these purposes. Some foods have been suggested to reduce absorption or reabsorption of toxic metals and to support natural detoxification pathways. Alpha-lipoic acid is an antioxidant that's in many foods, and it's made naturally in our bodies. Being both fat and water-soluble, it is readily absorbed from the gut and crosses cellular and blood-brain membrane barriers [22, 53]. Press J to jump to the feed. (ii) Alpha-lipoic acid is a powerful antioxidant that regenerates other antioxidants (e.g., vitamins E and C, and reduced glutathione) and has metal-chelating activity. It's not a "detox" reaction or from chelating heavy metals. Selenium depletion in the face of mercury exposure also depletes seleno-enzymes. Nonetheless, people claim moderate success using his regimen. Even if ALA can chelate mercury, it's not a compound that sounds likely to get eliminated afterwards. If you have confirmed that you have mercury toxicity, get a real chelating agent, preferably one actually backed by clinical evidence, and don't try an unproven treatment that doesn't sound likely to work and could be harmful. Alpha-Lipoic acid is commonly referred to as ALA and Thiocitic acid. I've been doing some reading on ALA supplementation (Alpha Lipoic Acid, not to be confused with Alpha Lineolic Acid for Omega-3 supplementation). Alpha‐lipoic acid (LA), a potent antioxidant, has been shown to be an effective treatment for diabetic neuropathy when given intravenously. However, caution is merited regarding soluble fiber; in contrast to the protection offered by insoluble fiber, flaxseed has resulted in increased intestinal absorption of cadmium [38]. CDN$ 5.54 shipping. Trying to keep its serum levels elevated is a failed proposition, and in fact it doesn't even free-float, rather, it's bound to lipoproteins. Alpha lipoic acid has helped me muscle twitches & neuropathy tremendously. Jarrow Formulas R-Alpha Lipoic Acid, Supports Energy, Cardio Vascular Health, 100 mg, 60 Caps. Has anyone else tried this for neuropathy? (iii) N-acetyl-cysteine (NAC), an orally available precursor of cysteine, is a chelator of toxic elements and may stimulate glutathione synthesis, particularly in the presence of vitamins C and E [54, 55, 56]. Advocates of ALA make claims that range from beneficial effects for treating conditions such as diabetes and HIV to enhancing weight loss. * It has important characteristics that contribute to liver, nerve, and eye health. When looking up information about this to gather case studies/evidence/etc. Some make it worse. * Alpha-Lipoic Acid. This is a unique & common antioxidant available in … "This may explain why the results of trials are confusing.I'm going to have to change when I take mine. In animals, it decreased lead absorption into bone, and inhibited the action of the delta-aminolevulinic acid dehydratase (ALAD) enzyme [47]. A more reasonable dosing regimen would be every 1.5 hours (and given my insomnia, I wake up at this rate anyway), which would result in fluctuations between around 125% and 25% dosing amounts. Alpha lipoic acid (ALA) is a powerful antioxidant which has been widely used in the treatment of different system diseases, such as cardiovascular and cerebrovascular diseases.

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